C Reactive Protein as a Marker of Asthma Control
نویسندگان
چکیده
CRP is a marker of inflammation and increased levels have been associated with aging, smoking, cardiovascular diseases, connective tissue disorders and chronic obstructive pulmonary disease (COPD). Asthma is defined as a state of chronic inflammation where various cellular elements are involved. It is reasonable to expect elevated CRP levels in this chronic inflammatory disease. Hs-CRP assays are capable of detecting low grade inflammation that is not possible by the standard CRP kits. Elevated CRP has been associated with acute exacerbation, deteriorating pulmonary function parameters and increased sputum eosinophil levels in asthma. We hope to explore the role of CRP in asthma in detail. Understanding the interplay between CRP and asthma may allow us to predict future exacerbation and better monitoring of asthma.
منابع مشابه
Serum C-reactive protein in asthma and its ability in predicting asthma control, a case-control study
Background: Increased serum high sensitive C-reactive protein (hs-CRP) in asthma and its association with disease severity has been investigated in many studies. This study aimed to determine serum hs-CRP status in asthma versus healthy controls and to examine its ability in predicting asthma control. Methods: Serum CRP was measured by ELISA method using a high sensitive CRP kit. Severity...
متن کاملThe Single Nucleotide Polymorphisms in the C-reactive Protein Gene: are they Biomarkers of Cardiovascular Risk?
Recent pre-clinical and clinical studies have revealed the C-reactive protein gene (CRP) is related to the degree of acute rise in plasma C-reactive protein (CRP) levels. Moreover, single nucleotide polymorphisms (SNPs) in the CRP gene could associate with increased risk of cancer, atherosclerosis, diabetes mellitus, bowel disease, rheumatoid arthritis, psoriasis, obstructive pulmonary disease,...
متن کاملProcalcitonin: A Reliable Marker for the Diagnosis of Neonatal Sepsis
Objective(s) In the last few years, serum procalcitonin has been proposed as an early marker of infections in neonates, with varying results. In this study, we aimed to investigate the value of procalcitonin, and C- reactive protein in establishing the diagnosis of neonatal sepsis. Materials and Methods Blood samples were collected at admission from 69 neonates with suspected infection (admi...
متن کاملInvestigating relationship between C- reactive protein and obesity in adults
Introduction: Association between plasma high-sensitivity C-reactive protein (CRP) concentrations and cardiovascular disease has been Investigated. C-reactive protein (CRP) is an acute phase reactant which is a marker of inflammation in the body. CRP is made by the liver in response to inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-α (TNFα). Adipose ti...
متن کاملEVALUATION OF SERUM CHITINASE-3 LIKE 1 PROTEIN AND C-REACTIVE PROTEIN LEVELS IN TYPE 2 DIABETES MELLITUS WITH CORONARY ARTERY DISEASE COMPARED TO DIABETIC AND HEALTHY CONTROL
Background: Diabetes mellitus, which is associated with elevated blood glucose, lipids and liver enzymes, may results in alterations in the production of inflammatory cytokines, including chitinase-3-like protein 1 (YKL-40) and high-sensitivity C-reactive protein (hs-CRP), which induce and promote complications of diabetes such as atherosclerosis.The aim of this study was to evaluate the serum ...
متن کاملC-reactive protein and other markers of inflammation in hemodialysis patients
Background: Hemodialysis patients are at greater risk of cardiovascular disease. Higher than expected cardiovascular morbidity and mortality in this population has been attributed to dislipidemia as well as inflammation. The causes of inflammation in hemodialysis patients are multifactorial. Several markers were used for the detection of inflammatory reaction in patients with chronic renal dise...
متن کامل